Decreased Serum 5‐ <scp>HT</scp> : Clinical Correlates and Regulatory Role in <scp>NMJ</scp> of <scp>MG</scp>
This first report of clinical characteristics and serum 5-HT levels from a cross-sectional cohort study on MG suggests that 5-HT plays a critical role in maintaining NMJ homeostasis. Additional cross-sectional data on more MG phenotypes and longitudinal monitoring data are needed to explore the role of 5-HT in the pathophysiological mechanisms of MG.
Authors
- Guanlian Hu
- Zhan Sun (ORCID: https://orcid.org/0000-0002-7182-8572)
- Jinru Wu
- Feng Gao (ORCID: https://orcid.org/0000-0002-4961-3495)
- Xue Zhao (ORCID: https://orcid.org/0000-0001-8985-1861)
- Haodong Shang
- Xin-Yue Zhou
- Shufan Chen (ORCID: https://orcid.org/0000-0002-9594-2222)
- Yingna Zhang (ORCID: https://orcid.org/0000-0002-8746-5788)
- Lulu Zhen
- Jiahui Wang (ORCID: https://orcid.org/0009-0004-8398-9869)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-2920-909X)
- Xiaoyan Zhu (ORCID: https://orcid.org/0000-0003-0122-3989)
- Yiren Wang (ORCID: https://orcid.org/0000-0003-1089-168X)
- Ying Peng (ORCID: https://orcid.org/0000-0001-6997-1102)
- Wei Guo (ORCID: https://orcid.org/0000-0003-1662-0194)
- Xiaoxiao Yu (ORCID: https://orcid.org/0000-0003-4103-2845)
- Xinru Shen
- Jie Lv (ORCID: https://orcid.org/0000-0003-2329-4817)
Institutions
- Zhengzhou University (CN)
- Zhengzhou University of Science and Technology (CN)
- First Affiliated Hospital of Henan University (CN)
- Zhengzhou Business University (CN)
Publication Details
- Journal
- Annals of Clinical and Translational Neurology
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1002/acn3.70222
- Primary Topic
- Myasthenia Gravis and Thymoma
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Henan University of Chinese Medicine
- Henan University