Fatty Acids Dysregulation Correlates with Lung Function in Idiopathic Pulmonary Fibrosis
In this study, we identified a dysregulation of cis-palmitoleic acid, oleic acid, elaidic acid, and arachidonic acid in IPF patients, indicating alterations in lipid metabolism and inflammatory pathways. Additionally, while arachidonic acid levels correlate with lung function, its diagnostic potential remains uncertain and warrants further evaluation in a larger patient population.
Authors
- Monica Gelzo (ORCID: https://orcid.org/0000-0002-1500-0746)
- Fabio Massimo Perrotta (ORCID: https://orcid.org/0000-0003-3771-5205)
- Vito D’Agnano (ORCID: https://orcid.org/0000-0001-6742-9387)
- Stefano Sanduzzi Zamparelli (ORCID: https://orcid.org/0000-0003-3336-7290)
- Mario Cazzola (ORCID: https://orcid.org/0000-0003-4895-9707)
- Maria Gabriella Matera (ORCID: https://orcid.org/0000-0002-5113-9235)
- Raffaella Pagliaro (ORCID: https://orcid.org/0009-0006-2902-3558)
- Filippo Scialò (ORCID: https://orcid.org/0000-0001-6648-1503)
- Andrea Bianco (ORCID: https://orcid.org/0000-0003-1320-294X)
- Giuseppe Castaldo
Institutions
- University of Rome Tor Vergata (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Fatebenefratelli Hospital (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- CEINGE Biotecnologie Avanzate Franco Salvatore (Italy) (IT)
- Ospedale Monaldi (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Lung
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1007/s00408-025-00852-0
- Citations
- 1
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Università degli Studi di Roma Tor Vergata