The kinetic behavior of matrine in pig intestinal lumen after oral administration and its physiologically based pharmacokinetic modeling
A dosage regimen of 70 mg/kg every 8 h was recommended to ensure a sufficient drug exposure.
Authors
- Yee‐Joo Tan (ORCID: https://orcid.org/0000-0002-2278-4497)
- Yang Jia (ORCID: https://orcid.org/0000-0003-2072-2898)
- FuHao Wang
- Dan Wan (ORCID: https://orcid.org/0000-0002-7474-6855)
- W. Zhang
- Danna Zhou (ORCID: https://orcid.org/0000-0001-9616-2976)
- Rui Li (ORCID: https://orcid.org/0000-0003-2318-9232)
- Bo Yang (ORCID: https://orcid.org/0000-0003-0680-1469)
- Daojin Yu
- XiaoLing Lv
- Siqi Ma
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
- Chinese Academy of Sciences (CN)
- Animal Science Research Institute (CN)
- Institute of Subtropical Agriculture (CN)
- Fujian Electric Power Survey & Design Institute (CN)
- Ministry of Agriculture and Rural Affairs (CN)
- Hubei Academy of Agricultural Sciences (CN)
- Fujian Agriculture and Forestry University (CN)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3389/fvets.2025.1620161
- Primary Topic
- Analytical Chemistry and Chromatography
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China