Unveiling the anti-inflammatory potential of olive leaf phenolic extracts in diabetes-related endothelial dysfunction
These findings support the anti-inflammatory activity of olive leaf polyphenols and highlight the potential of Changlot Real and Picual extracts in mitigating endothelial dysfunction associated with diabetes. By modulating the NF-kB-VCAM-1 axis, these compounds may attenuate endothelial activation, warranting further investigation into their possible role in the prevention or mitigation of diabetes-related vascular complications.
Authors
- Davide Viola
- Gloria Formoso (ORCID: https://orcid.org/0000-0001-8692-8827)
- Ilaria Cappellacci
- Beatriz Martín-García (ORCID: https://orcid.org/0000-0002-6367-1333)
- Caterina Pipino
- Vito Verardo (ORCID: https://orcid.org/0000-0003-0723-5163)
- Nadia Di Pietrantonio (ORCID: https://orcid.org/0000-0001-6604-0804)
- Ana María Gómez‐Caravaca (ORCID: https://orcid.org/0000-0003-1837-269X)
- Małgorzata Elżbieta Zujko (ORCID: https://orcid.org/0000-0002-0410-3539)
- Assunta Pandolfi (ORCID: https://orcid.org/0000-0003-4135-7631)
Institutions
- Medical University of Silesia (PL)
- Universidad de Granada (ES)
- University of Chieti-Pescara (IT)
- Parque Tecnológico de la Salud (ES)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3389/fendo.2025.1671932
- Citations
- 1
- Primary Topic
- Edible Oils Quality and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.94