Microvascular changes in children with MIS-C: a monocentric exploratory study using comparative nailfold capillaroscopy

Nailfold capillaroscopy revealed notable microvascular alterations in children with MIS-C, including increased tortuosity, dilated capillaries, and disorganization. These findings suggest that NFC may serve as a useful non-invasive tool for detecting endothelial dysfunction and early microvascular involvement in MIS-C. Importantly, given the current rarity of MIS-C cases in the post-pandemic era, this study provides a unique and timely contribution, offering one of the few systematic evaluations of microvascular alterations in pediatric MIS-C and establishing a valuable reference point for future comparative research in pediatric vasculopathies.