Evaluating the risk and risk factors of dysautonomia as a post-acute sequelae of COVID-19: a secondary analysis of a matched case–control dataset
PASC dysautonomia is rare in ADSM but associated with increased care utility and often prolonged diagnostic pathways. Important demographic and COVID-19 specific risk factors are associated with the development of PASC dysautonomia. PASC dysautonomia has significant differences in risk factors as compared to non-PASC dysautonomia, warranting further examination. These findings may support clinician awareness and prognostication and prompt further research on the pathophysiology and management of these conditions.
Authors
- Timothy H. Burgess (ORCID: https://orcid.org/0000-0003-1247-8370)
- Tracey Pérez Koehlmoos (ORCID: https://orcid.org/0000-0003-1377-8615)
- James D. Mancuso (ORCID: https://orcid.org/0000-0002-0717-8202)
- Caryn Stern (ORCID: https://orcid.org/0000-0002-9914-9889)
- Simon Pollett (ORCID: https://orcid.org/0000-0002-4450-7028)
- Edward Parmelee
- Benjamin C. Pierson (ORCID: https://orcid.org/0009-0004-8642-293X)
- Megan Clare Craig-Kuhn (ORCID: https://orcid.org/0000-0002-5400-8193)
- David Saunders (ORCID: https://orcid.org/0000-0003-0946-1164)
- Erica Sercy (ORCID: https://orcid.org/0000-0002-7975-8601)
- David R. Tribble (ORCID: https://orcid.org/0000-0003-3077-9505)
- Laveta Stewart
- Brock Graham
- Amber Michel
Institutions
- Henry M. Jackson Foundation (US)
- Uniformed Services University of the Health Sciences (US)
- Joint Base San Antonio (US)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.3389/fneur.2025.1653175
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Uniformed Services University of the Health Sciences