LNCRNA-GASS: A PROSPECTIVE BIOMARKER FOR SEPSIS THERAPY

Sepsis, characterized by life-threatening organ impairment triggered by aberrant host reaction to infection, continues to pose a global health challenge with consistently elevated rates of morbidity and mortality. Long non-coding RNAs (lncRNAs) have emerged as crucial modulators in various biological processes, including the development of sepsis. Among these molecules, lncRNA-GASS has attracted growing interest as a promising biomarker of sepsis. This review compiles the current understanding of lncRNA-GASS, covering its regulatory mechanisms in sepsis, its connections to sepsis-induced organ damage, and its potential as a diagnostic/prognostic biomarker for sepsis treatment.