11α-hydroxyprogesterone dampens lung metastasis via EMT modulation in PyMT-induced breast cancer murine model
These findings suggest that 11α-OHP may suppress breast cancer metastasis by modulating EMT, highlighting its potential as a therapeutic target for preventing metastatic progression.
Authors
- Ahyoung Song (ORCID: https://orcid.org/0000-0001-6654-0235)
- Moeka Mukae (ORCID: https://orcid.org/0009-0007-6541-9936)
- Namwoog Kim (ORCID: https://orcid.org/0009-0005-8298-4422)
- Beum‐Soo An (ORCID: https://orcid.org/0000-0002-7052-6564)
- Eui‐Ju Hong (ORCID: https://orcid.org/0000-0001-9640-8841)
- Jinhee Lee (ORCID: https://orcid.org/0000-0002-2359-6383)
Institutions
- Chungnam National University (KR)
- Pusan National University (KR)
Publication Details
- Journal
- Laboratory Animal Research
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1186/s42826-025-00259-1
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- Chungnam National University
- National Research Foundation of Korea