Acid-Catalyzed Three-Component Bicyclization for the Synthesis of Quinazoline Fused Imidazole-2-thione Derivatives with a Tetrasubstituted Carbon Center
An acid-catalyzed three-component bicyclization strategy has been developed for constructing novel 3,9-dihydroimidazo[5,1- b]quinazoline-1(2 H)-thione derivatives from readily available arylglyoxal monohydrates, 2-aminobenzylamine, and isothiocyanates
Authors
- Kewei Hu
- Jinxing Zhang (ORCID: https://orcid.org/0000-0001-8977-5678)
- Qun Cai (ORCID: https://orcid.org/0000-0002-7853-9570)
- Jiang-Yan Xue
- Duoluo Guo
Institutions
- Wuhan University of Science and Technology (CN)
Publication Details
- Published
- 2025-10-14
- DOI
- https://doi.org/10.22541/au.176040730.00109785/v1
- Primary Topic
- Quinazolinone synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00