The Stability of Never-Thawed Serum Biospecimens Stored in Vapor-Phase Liquid Nitrogen: Select Analytes from the National Health and Nutrition Examination Survey, 1999–2000 and 2005–2006
Multipronged analysis showed that most differences are within acceptable ranges based on standard laboratory criteria for assessing accuracy, precision, and reproducibility. Results suggest future measurements and subsequent statistical analyses of stored serum specimens should be valid.
Authors
- Carissa D. Powers
- Lanqing Wang (ORCID: https://orcid.org/0000-0001-6620-7096)
- Renee Storandt (ORCID: https://orcid.org/0000-0001-7098-8171)
- Ekaterina Mineva (ORCID: https://orcid.org/0000-0002-9079-0856)
- Christine M Pfeiffer (ORCID: https://orcid.org/0000-0003-3438-5191)
- Geraldine M. McQuillan
- Eric A. Tolliver
- Rosemary L. Schleicher (ORCID: https://orcid.org/0000-0002-4520-0749)
- Connie S. Sosnoff (ORCID: https://orcid.org/0000-0001-9162-633X)
- Jan Drobeniuc (ORCID: https://orcid.org/0000-0002-0735-8115)
- Jennifer Rammon (ORCID: https://orcid.org/0000-0003-1602-8465)
Institutions
- Centers for Disease Control and Prevention (US)
- United States Food and Drug Administration (US)
- National Center for Health Statistics (US)
- National Center for Environmental Health (US)
- National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention (US)
Publication Details
- Journal
- Biopreservation and Biobanking
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1177/19475535251382352
- Primary Topic
- Clinical Laboratory Practices and Quality Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00