<i>EGFR</i> <scp>T790M</scp> Mutations in Conventional and Langerhans Cell‐Rich Variants of <scp>CEOT</scp> : Unveiling Molecular Differences and Clinical Implications

The identification of EGFR c.2369C>T (p.T790M) mutations in both variants underscores its significant role in CEOT pathogenesis and suggests potential implications for targeted therapies. This comprehensive analysis enhances our understanding of the molecular landscape of CEOT variants and highlights the necessity for tailored diagnostic and treatment strategies.

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Publication Details

Journal
Oral Diseases
Published
2025-10-13
DOI
https://doi.org/10.1111/odi.70111
Primary Topic
Oral and Maxillofacial Pathology
Type
article
Field-Weighted Citation Impact
0.00
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article

EGFR T790M Mutations in Conventional and Langerhans Cell‐Rich Variants of CEOT : Unveiling Molecular Differences and Clinical Implications

Jiang Xue, Lisha Sun, Wenyi Zhang, Zhipeng Sun
Oral Diseases
Oral and Maxillofacial Pathology
article

EGFR T790M Mutations in Conventional and Langerhans Cell‐Rich Variants of CEOT : Unveiling Molecular Differences and Clinical Implications

Jiang Xue, Lisha Sun, Wenyi Zhang, Zhipeng Sun
article en

Abstract

The identification of EGFR c.2369C>T (p.T790M) mutations in both variants underscores its significant role in CEOT pathogenesis and suggests potential implications for targeted therapies. This comprehensive analysis enhances our understanding of the molecular landscape of CEOT variants and highlights the necessity for tailored diagnostic and treatment strategies.

Oral Diseases
King University (US), Peking University (CN), National Clinical Research Center for Digestive Diseases (CN), Peking University People's Hospital (CN)
Openalex Percentile: Top 60%
Oral and Maxillofacial Pathology
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