The synergistic anti‐inflammatory effect of pterostilbene and honokiol on <scp>LPS</scp>‐stimulated <scp>PMA</scp>‐differentiated <scp>THP</scp>‐1 macrophages

Pt and Ho exert synergistic anti-inflammatory effects in macrophages and can be safely used within systemically acceptable concentration limits in cosmetic formulations. These findings support their development as a multifunctional combination targeting inflammation-related skin conditions, while underscoring the need for further investigation into dermal safety, optimized dosing strategies and broader mechanistic pathways.