Nuclear Imaging and Echocardiographic Findings in Hypertrophic Cardiomyopathy with and without ATTR-CM

In this real-world study, a high level of concordance was seen in cardiac uptake grading on planar versus SPECT imaging, with discordant findings only observed with [<sup>99m</sup>Tc]Tc-PYP. The findings support the use of these imaging tools to facilitate ATTR-CM screening in clinical practice. Further studies should investigate differences across tracers used in ATTR-CM screening. NCT03842163.

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Publication Details

Journal
ESC Heart Failure
Published
2025-10-13
DOI
https://doi.org/10.1002/ehf2.15440
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
0.00

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article

Nuclear Imaging and Echocardiographic Findings in Hypertrophic Cardiomyopathy with and without ATTR-CM

Roberto Barriales‐Villa, Perry Elliott, Carmen Munteanu, Emmanuel Itti et al.
ESC Heart Failure
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Nuclear Imaging and Echocardiographic Findings in Hypertrophic Cardiomyopathy with and without ATTR-CM

Roberto Barriales‐Villa, Perry Elliott, Carmen Munteanu, Emmanuel Itti, Pablo García‐Pavía, Denis Keohane, Francesco Cappelli, Pablo Mallaina, Nicolas Piriou, Catherine Bahus, F. Moral, Thibaud Damy
article en

Abstract

In this real-world study, a high level of concordance was seen in cardiac uptake grading on planar versus SPECT imaging, with discordant findings only observed with [<sup>99m</sup>Tc]Tc-PYP. The findings support the use of these imaging tools to facilitate ATTR-CM screening in clinical practice. Further studies should investigate differences across tracers used in ATTR-CM screening. NCT03842163.

ESC Heart FailureVol. 12(6)
Inserm (FR), Pfizer (United States) (US), Université Paris-Est Créteil (FR), Universidad Francisco de Vitoria (ES), Spanish National Centre for Cardiovascular Research (ES), Assistance Publique – Hôpitaux de Paris (FR), Hospital Universitario Puerta de Hierro Majadahonda (ES), Azienda Ospedaliero-Universitaria Careggi (IT), Hôpitaux Universitaires Henri-Mondor (FR), Complexo Hospitalario Universitario A Coruña (ES), Institut du Thorax (FR), Institut Mondor de Recherche Biomédicale (FR), University College London (GB)
Pfizer
Openalex Percentile: Top 74%
Amyloidosis: Diagnosis, Treatment, Outcomes
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