Evaluating AI performance in infectious disease education: a comparative analysis of ChatGPT, Google Bard, Perplexity AI, Microsoft Copilot, and Meta AI

AI platforms offer potential in infectious disease education but demonstrate limitations in pharmacotherapy decision-making, particularly in antimicrobial selection and dosing accuracy. ChatGPT 3.5 performed best but lacked response stability, while Microsoft Copilot showed greater consistency but lacked nuanced therapeutic reasoning. Further research is needed to improve AI-driven decision support systems for medical education and clinical applications through clinical trials, evaluation of real-world patient data, and assessment of long-term stability.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-10-13
DOI
https://doi.org/10.3389/fmed.2025.1679153
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00

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article

Evaluating AI performance in infectious disease education: a comparative analysis of ChatGPT, Google Bard, Perplexity AI, Microsoft Copilot, and Meta AI

Omar Awad Alsaidan, Azfar Athar Ishaqui, Tauqeer Hussain Mallhi, Muhammad Bilal Maqsood et al.
Frontiers in Medicine
Artificial Intelligence in Healthcare and Education
article

Evaluating AI performance in infectious disease education: a comparative analysis of ChatGPT, Google Bard, Perplexity AI, Microsoft Copilot, and Meta AI

Omar Awad Alsaidan, Azfar Athar Ishaqui, Tauqeer Hussain Mallhi, Muhammad Bilal Maqsood, Narendar Kumar, Sami I. Alzarea, Abdullah Salah Alanazi, Sultan M. Alshahrani, Abdulaziz Ibrahim Alzarea, Hassan H. Alhassan, Aseel Awad Alsaidan, Muhammad Imran
article en

Abstract

AI platforms offer potential in infectious disease education but demonstrate limitations in pharmacotherapy decision-making, particularly in antimicrobial selection and dosing accuracy. ChatGPT 3.5 performed best but lacked response stability, while Microsoft Copilot showed greater consistency but lacked nuanced therapeutic reasoning. Further research is needed to improve AI-driven decision support systems for medical education and clinical applications through clinical trials, evaluation of real-world patient data, and assessment of long-term stability.

Frontiers in MedicineVol. 12
St. Gregory's University (US), University of Sindh (PK), Iqra University (PK), Jouf University (SA), Ministry of Health (SA), Taylor's University (MY), King Khalid University (SA)
King Khalid University
Openalex Percentile: Top 79%
Artificial Intelligence in Healthcare and Education
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Evaluating AI performance in infectious disease education: a comparative analysis of ChatGPT, Google Bard, Perplexity AI, Microsoft Copilot, and Meta AI — Omar Awad Alsaidan, Azfar Athar Ishaqui, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS