Allium hookeri root extract restores streptozotocin-induced pancreatic β-cells dysfunction in a type 1 diabetic rat model
AHRE can facilitate β-cell regeneration in the impaired pancreatic islets through STZ by reducing oxidative stress markers and apoptosis in pancreatic tissue. Owing to pancreatic β-cells are susceptible to oxidative stress, the protective and enhancing effects of AHRE on the apoptosis and regeneration of these cells may be a significant mechanism for its hypoglycemic effect.
Authors
- Sung Hyen Lee (ORCID: https://orcid.org/0000-0002-7886-4752)
- Jong‐Sik Jin (ORCID: https://orcid.org/0000-0002-1387-6226)
- Hyun Ju Kim (ORCID: https://orcid.org/0000-0002-9466-7126)
- Miran Kang (ORCID: https://orcid.org/0000-0002-9765-7564)
- Seong-Soo Roh
Institutions
- Daegu Haany University (KR)
- Rural Development Administration (KR)
- World Institute of Kimchi (KR)
- Jeonbuk National University (KR)
Publication Details
- Journal
- Food & Nutrition Research
- Published
- 2025-10-13
- DOI
- https://doi.org/10.29219/fnr.v69.12104
- Primary Topic
- Garlic and Onion Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00