A dual attention and cross layer fusion network with a hybrid CNN and transformer architecture for medical image segmentation

Medical image segmentation is a crucial technology for disease diagnosis and treatment planning. However, current approaches face challenges in capturing global semantic dependencies and integrating cross-layer features. While Convolutional Neural Networks (CNNs) excel at extracting local features, they struggle with long-range dependencies; Transformers effectively model global context but may compromise spatial details. To address these limitations, this paper proposes a novel hybrid CNN-Transformer architecture, Dual Attention and Cross-layer Fusion Network (DCF-Net). Based on an encoder-decoder framework, DCF-Net introduces two key modules: the Channel-Adaptive Sparse Attention (CASA) module and the Synergistic Skip-connection and Cross-layer Fusion (SSCF) module. Specifically, CASA enhances semantic modeling by filtering critical features and focusing on anatomically important regions, while SSCF enables effective hierarchical feature fusion by bridging encoder-decoder representations. Extensive experiments on the Synapse, ACDC, and ISIC2017 datasets demonstrate that DCF-Net achieves state-of-the-art performance without pre-training. This work highlights the value of cross-layer fusion and attention mechanism, providing a robust and generalizable solution for medical image segmentation tasks.

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Publication Details

Journal
Scientific Reports
Published
2025-10-13
DOI
https://doi.org/10.1038/s41598-025-19563-w
Citations
1
Primary Topic
AI in cancer detection
Type
article
Field-Weighted Citation Impact
2.48

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article

A dual attention and cross layer fusion network with a hybrid CNN and transformer architecture for medical image segmentation

Zhengyou Liang, X. Lucas Lu, Jiahong Chen
1 citations
Scientific Reports
AI in cancer detection
2.48
article

A dual attention and cross layer fusion network with a hybrid CNN and transformer architecture for medical image segmentation

Zhengyou Liang, X. Lucas Lu, Jiahong Chen
article en
1 citations

Abstract

Medical image segmentation is a crucial technology for disease diagnosis and treatment planning. However, current approaches face challenges in capturing global semantic dependencies and integrating cross-layer features. While Convolutional Neural Networks (CNNs) excel at extracting local features, they struggle with long-range dependencies; Transformers effectively model global context but may compromise spatial details. To address these limitations, this paper proposes a novel hybrid CNN-Transformer architecture, Dual Attention and Cross-layer Fusion Network (DCF-Net). Based on an encoder-decoder framework, DCF-Net introduces two key modules: the Channel-Adaptive Sparse Attention (CASA) module and the Synergistic Skip-connection and Cross-layer Fusion (SSCF) module. Specifically, CASA enhances semantic modeling by filtering critical features and focusing on anatomically important regions, while SSCF enables effective hierarchical feature fusion by bridging encoder-decoder representations. Extensive experiments on the Synapse, ACDC, and ISIC2017 datasets demonstrate that DCF-Net achieves state-of-the-art performance without pre-training. This work highlights the value of cross-layer fusion and attention mechanism, providing a robust and generalizable solution for medical image segmentation tasks.

Scientific ReportsVol. 15(1)
Guangxi University (CN), Guangxi University of Chinese Medicine (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 8%
AI in cancer detection
2.48
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