A dual attention and cross layer fusion network with a hybrid CNN and transformer architecture for medical image segmentation
Medical image segmentation is a crucial technology for disease diagnosis and treatment planning. However, current approaches face challenges in capturing global semantic dependencies and integrating cross-layer features. While Convolutional Neural Networks (CNNs) excel at extracting local features, they struggle with long-range dependencies; Transformers effectively model global context but may compromise spatial details. To address these limitations, this paper proposes a novel hybrid CNN-Transformer architecture, Dual Attention and Cross-layer Fusion Network (DCF-Net). Based on an encoder-decoder framework, DCF-Net introduces two key modules: the Channel-Adaptive Sparse Attention (CASA) module and the Synergistic Skip-connection and Cross-layer Fusion (SSCF) module. Specifically, CASA enhances semantic modeling by filtering critical features and focusing on anatomically important regions, while SSCF enables effective hierarchical feature fusion by bridging encoder-decoder representations. Extensive experiments on the Synapse, ACDC, and ISIC2017 datasets demonstrate that DCF-Net achieves state-of-the-art performance without pre-training. This work highlights the value of cross-layer fusion and attention mechanism, providing a robust and generalizable solution for medical image segmentation tasks.
Authors
- Zhengyou Liang
- X. Lucas Lu (ORCID: https://orcid.org/0000-0001-6905-6887)
- Jiahong Chen (ORCID: https://orcid.org/0009-0009-0306-0248)
Institutions
- Guangxi University (CN)
- Guangxi University of Chinese Medicine (CN)
Publication Details
- Journal
- Scientific Reports
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1038/s41598-025-19563-w
- Citations
- 1
- Primary Topic
- AI in cancer detection
- Type
- article
- Field-Weighted Citation Impact
- 2.48
Funders
- National Natural Science Foundation of China