Effects of Lavandula angustifolia Extract and Copper Oxide Nanoparticles (CuO-NP) on Some Biochemical Outcomes in Mouse Blood Tissue

Our study is on the protective effect of lavender oil on oxidative stress caused by copper oxide nanoparticles (CuO NPs). For this purpose, 0.5 mg/kg body weight L. angustifolia, 5.0 mg/kg body weight CuO NPs and their mixtures (0.5 mg/kg body weight L. angustifolia +5 mg/kg body weight CuO NPs) were administered to mice by gavage method for 14 days. At the end of the time, antioxidant activities such as biochemical parameters (ALT, AST, T. Prot, Cholesterol) in mouse blood tissue and their combined effects on copper accumulation in kidney and liver tissues were investigated in male Swiss albino mice. The study results showed that copper accumulation in liver and kidney tissue increased significantly. While ALT and AST values in blood tissue increased compared to control, significant decreases were observed in T. Protein and cholesterol levels. These results showed us that lavender oil was significantly effective in homeostatic effects against any toxicity in mouse blood tissue.