How long is long enough? Timing of pre-conceptional remission predicts relapse risk during pregnancy in IBD
This large multicenter study demonstrates that disease activity within 6 months before conception significantly increases the risk of relapse during pregnancy in women with IBD. Our study is the first to assess both the pre-conceptional disease course and a broad set of known risk factors in a real-world cohort.
Authors
- Henk Groen (ORCID: https://orcid.org/0000-0002-6629-318X)
- Birgit Hoekstra
- D G Bouwknegt (ORCID: https://orcid.org/0000-0002-6208-2967)
- Marijn C. Visschedijk (ORCID: https://orcid.org/0000-0001-7277-7677)
- Gerard D. H. Dijkstra (ORCID: https://orcid.org/0000-0003-4563-7462)
- Hylke C. Donker (ORCID: https://orcid.org/0000-0001-5648-9552)
- Willemijn A. van Dop (ORCID: https://orcid.org/0000-0002-4653-6594)
- C. Janneke van der Woude (ORCID: https://orcid.org/0000-0003-3875-6957)
- Tjebbe Tauber
- Bram van Es (ORCID: https://orcid.org/0000-0003-4667-1304)
Institutions
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- University of Groningen (NL)
- Utrecht University (NL)
- Erasmus MC (NL)
- Radboud University Medical Center (NL)
- University Medical Center Utrecht (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Journal of Crohn s and Colitis
- Published
- 2025-09-30
- DOI
- https://doi.org/10.1093/ecco-jcc/jjaf176
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00