Switching to subcutaneous administration may offer more profound remission compared to intensified intravenous therapy in patients with inflammatory bowel disease and partial response following induction with intravenous vedolizumab: the PRIVEDO stud

In IBD patients with partial response to IV VDZ induction, switching to SC VDZ may lead to more profound remission than continuing IV optimization.

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Publication Details

Journal
Journal of Crohn s and Colitis
Published
2025-09-27
DOI
https://doi.org/10.1093/ecco-jcc/jjaf175
Primary Topic
Inflammatory Bowel Disease
Type
article
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article

Switching to subcutaneous administration may offer more profound remission compared to intensified intravenous therapy in patients with inflammatory bowel disease and partial response following induction with intravenous vedolizumab: the PRIVEDO stud

Filippo Mocciaro, Ambrogio Orlando, Walter Fries, G. Mistretta et al.
Journal of Crohn s and Colitis
Inflammatory Bowel Disease
article

Switching to subcutaneous administration may offer more profound remission compared to intensified intravenous therapy in patients with inflammatory bowel disease and partial response following induction with intravenous vedolizumab: the PRIVEDO stud

Filippo Mocciaro, Ambrogio Orlando, Walter Fries, G. Mistretta, Samantha L. Morello, Sara Renna, B. Scrivo, Mauro Grova, Raffaele Li Voti, Fabio Salvatore Macaluso, Concetta Ferracane, Emiliano Giangreco, P Melatti, Angelo Casà, Anna Viola, Maria Giovanna Minissale, Simona Di, Maria Cappello, Stefano Muscarella, Samuele Armetta
article en

Abstract

In IBD patients with partial response to IV VDZ induction, switching to SC VDZ may lead to more profound remission than continuing IV optimization.

Journal of Crohn s and ColitisVol. 19(10)
Ospedale Vincenzo Cervello (IT), Ospedale Sant Antonio (IT), Hospital Universitario Araba (ES), University of Palermo (AR), Azienda Ospedaliera Universitaria Policlinico "G. Martino" (IT), Azienda di Rilievo Nazionale ed Alta Specializzazione (IT), Azienda Ospedaliero Universitaria Policlinico "G.Rodolico - San Marco" (IT), Ospedale Buccheri la Ferla Fatebenefratelli (IT), University of Palermo (IT)
Openalex Percentile: Top 69%
Inflammatory Bowel Disease
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Switching to subcutaneous administration may offer more profound remission compared to intensified intravenous therapy in patients with inflammatory bowel disease and partial response following induction with intravenous vedolizumab: the PRIVEDO stud — Filippo Mocciaro, Ambrogio Orlando, et al. · Journal of Crohn s and Colitis (2025) | TGRS Research Map | TGRS