Striae gravidarum in the Han Chinese pregnant population: identifying genetic markers and risk factors through a prospective cohort study
The study presents a predictive model for SG risk that incorporating non-modifiable factors like family history and skin type, and modifiable factors such as pre-pregnancy weight and BMI. The findings offer valuable insights into the genetic underpinnings of SG and have the potential to inform patient counseling on strategies for risk mitigation. Moreover, the identified risk factors can enhance patient counseling, while therapeutic interventions should be specifically tailored to options that are safe during pregnancy or suitable for the postpartum period.
Authors
- Jianguo Chen (ORCID: https://orcid.org/0000-0003-4102-8934)
- Lidan Xiong (ORCID: https://orcid.org/0000-0001-8534-4408)
- Lifeng Yang (ORCID: https://orcid.org/0000-0001-5175-7589)
- Xiuju Dong
- Yun Han (ORCID: https://orcid.org/0000-0002-3847-3757)
- Hailun He (ORCID: https://orcid.org/0000-0003-3744-7319)
- Li Li (ORCID: https://orcid.org/0000-0003-4527-5705)
- Yinshu Wang
Institutions
- National Medical Products Administration (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Third People's Hospital of Chengdu (CN)
- Science and Technology Department of Sichuan Province (CN)
- Hangzhou DAC Biotech (China) (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1186/s12884-025-08144-4
- Primary Topic
- Dermatologic Treatments and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00