Risk Factors for Lower Adherence to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors for Non-Small Cell Lung Cancer: A Nationwide Retrospective Cohort Study in Japan
Adherence to EGFR-TKIs was generally high, but the findings support tailored adherence strategies, especially for older patients and for those with a higher number of concomitant oral medications, including medication review to reduce pill burden and proactive support for swallowing difficulties.
Authors
- Shinji Akiyama
- Sadamu YAMAMOTO (ORCID: https://orcid.org/0000-0001-9080-4747)
- Yasutaka Ihara (ORCID: https://orcid.org/0000-0003-2538-6328)
- Megumi Mizutani
- Naoto Okada (ORCID: https://orcid.org/0000-0003-2476-9191)
- Yuki Shimomura (ORCID: https://orcid.org/0009-0006-8474-602X)
Publication Details
- Journal
- Oncology
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1159/000548812
- Citations
- 1
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 1.52