Reliability of blood inflammatory markers at constant real-life workloads over time: Study protocol
Knowledge of and models currently describing the pathological role of systemic inflammatory biomarkers are based on highly-controlled laboratory rat experiments. This study has the strength of assessing a human population under real-life conditions. The major challenge is in participant recruitment given the intensive and complex study design. The results of this study could provide fundamentals for initiating a cohort study and be used for developing work-related stress-recovery concepts for occupations with different physical demands to identify workers who may be at risk for developing WMSDs. German Clinical Trials Register (DRKS00031872, 25 May 2023).
Authors
- Benjamin Steinhilber (ORCID: https://orcid.org/0000-0001-9622-6511)
- Florestan Wagenblast (ORCID: https://orcid.org/0000-0003-1955-6810)
- Frank Uhlemann
- Thomas Läubli (ORCID: https://orcid.org/0000-0003-4137-1599)
- Tessy Luger (ORCID: https://orcid.org/0000-0001-5718-251X)
- Monika A. Rieger (ORCID: https://orcid.org/0000-0002-7855-3663)
- Barbara Munz (ORCID: https://orcid.org/0000-0002-4582-6119)
- Manfred Schmolz
Institutions
- University Children's Hospital Tübingen (DE)
- University of Tübingen (DE)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1371/journal.pone.0334244
- Primary Topic
- Musculoskeletal pain and rehabilitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00