Leprosy relapse after multidrug therapy: Systematic review and meta-analysis
The prevalence of relapse varied according to the geographic location and type of multidrug therapy, with substantial heterogeneity across studies. These findings suggest that factors such as individual patient characteristics, treatment adherence, and capacity for healthcare services may have influenced the outcomes observed in this review.
Authors
- Vilanice Alves de Araújo Püschel (ORCID: https://orcid.org/0000-0001-6375-3876)
- Jack Roberto Silva Fhon (ORCID: https://orcid.org/0000-0002-1880-4379)
- Fabiane Verônica da Silva (ORCID: https://orcid.org/0000-0002-6922-4120)
- Zélia Anastácio (ORCID: https://orcid.org/0000-0002-3786-6559)
- Silvana Margarida Benevides Ferreira (ORCID: https://orcid.org/0000-0001-7421-5803)
- Pãmela Rodrigues de Souza Silva (ORCID: https://orcid.org/0000-0002-3602-603X)
- Omar Ariel Espinosa (ORCID: https://orcid.org/0000-0002-0912-9527)
- Juliana Akie Takahashi (ORCID: https://orcid.org/0000-0002-6190-5095)
- Gutembergue Santos de Sousa (ORCID: https://orcid.org/0000-0003-3672-4388)
- Roberta Olmo Pinheiro (ORCID: https://orcid.org/0000-0001-8471-4227)
- Eric Brito Ferraz
Institutions
- Universidad de Panamá (PA)
- Universidade de São Paulo (BR)
- Universidade Federal de Mato Grosso (BR)
- Microsoft (Brazil) (BR)
- Hospital Amaral Carvalho (BR)
- Evidence Based Research (United States) (US)
- ID Genomics (United States) (US)
- Sociedade Brasileira de Imunologia (BR)
- Fundação Oswaldo Cruz (BR)
- University of Minho (PT)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1371/journal.pntd.0011870
- Primary Topic
- Leprosy Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministério da Ciência, Tecnologia e Inovação
- Conselho Nacional de Desenvolvimento Científico e Tecnológico