The severity of depressive symptoms as a mediator in the sleep-osteoarthritis risk pathway: insights from the ELSA cohort
Poor sleep quality and short sleep duration are independent risk factors for incident OA in middle-aged and older adults. The severity of depressive symptoms partially mediates this relationship. Maintaining optimal sleep duration (8 h), improving sleep quality, and addressing depressive symptoms may help reduce OA risk.
Authors
- Lincheng Duan (ORCID: https://orcid.org/0000-0003-1937-1605)
- Xin Duan (ORCID: https://orcid.org/0000-0002-5775-9670)
- Junbo Wang (ORCID: https://orcid.org/0000-0002-9776-1441)
- Li Chen (ORCID: https://orcid.org/0000-0001-9356-6924)
- Zhichao Chen (ORCID: https://orcid.org/0000-0002-9884-0002)
Institutions
- Integrated Chinese Medicine (China) (HK)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-10-13
- DOI
- https://doi.org/10.3389/fnut.2025.1676763
- Citations
- 1
- Primary Topic
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47