<i>ADIPOQ</i> genotypes and haplotypes, circulating adiponectin levels and responsiveness to antihypertensive therapy in preeclampsia
Nonresponsive patients with PE showed higher plasma adiponectin levels than responsive patients, the TG genotype of the rs2241766 SNP was more frequent in the responsive patients with PE when compared to nonresponsive patients. Genotypes of rs17300539, rs266729, rs2241766, and rs1501299 SNPs and haplotypes may affect adiponectin levels in patients with PE classified as nonresponsive to antihypertensive therapy.
Authors
- Marcelo R. Luizon (ORCID: https://orcid.org/0000-0002-8331-3525)
- Valéria C. Sandrim (ORCID: https://orcid.org/0000-0002-6168-7470)
- Ana C. Palei (ORCID: https://orcid.org/0000-0002-2669-5301)
- Ricardo de Carvalho Cavalli (ORCID: https://orcid.org/0000-0001-5010-4914)
- Daniela A. Pereira (ORCID: https://orcid.org/0000-0001-5491-6709)
- Rafael Castro
Institutions
- Universidade Federal de Minas Gerais (BR)
- Universidade de São Paulo (BR)
- University of Mississippi Medical Center (US)
- Federal Center for Technological Education of Minas Gerais (BR)
- Universidade Estadual Paulista (Unesp) (BR)
Publication Details
- Journal
- Pharmacogenomics
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1080/14622416.2025.2572286
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00