Comparison of 3D culture systems on mesenchymal stem cell longevity, regenerative potential, and secretome production
This study highlights the critical influence of culture systems on scaling robust MSC-based therapies and introduces a biomimetic platform that represents a potential scalable strategy for producing high-potency and robust regenerative therapies.
Authors
- Adam J. Mellott (ORCID: https://orcid.org/0000-0002-7545-3763)
- Jennifer L. Robinson (ORCID: https://orcid.org/0000-0002-5421-2370)
- Heather E. Decker
- Christopher A. Neal (ORCID: https://orcid.org/0000-0002-9691-2746)
- Jacob Hodge (ORCID: https://orcid.org/0000-0002-6165-3932)
- Aidyn Medina-Lopez
Institutions
- University of Washington (US)
- Korea Naval Academy (KR)
- University of Kansas Medical Center (US)
Publication Details
- Journal
- Regenerative Medicine
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1080/17460751.2025.2572177
- Citations
- 1
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 1.63