Prevalence, Risk Factors, and Endoscopic Findings of Helicobacter pylori Infection Among Lebanese Patients Undergoing Gastroscopy: A Retrospective Study from a Single Tertiary Center

(1) Background: Gastric cancer continues to pose a significant public health challenge, with its incidence influenced by various factors, including <i>Helicobacter pylori</i> (<i>H. pylori</i>) infection. In Lebanon, data on <i>H. pylori</i> prevalence and its associated risk factors remain limited. This study aimed to determine the prevalence of <i>H. pylori</i> infection among Lebanese outpatients presenting with gastrointestinal symptoms undergoing gastroscopy, to explore correlations between the infection and demographic and clinical variables, and to evaluate the prevalence of associated conditions such as gastritis, duodenitis, and intestinal metaplasia. (2) Methods: Using a retrospective design, data from 786 patients admitted at a hospital in Beirut over a three-year period were extracted from records. (3) Results: The prevalence of <i>H. pylori</i> infection was 29.6% despite 91.5% of patients showing signs of gastritis on endoscopy. The infection showed significant associations with erosive gastritis, non-erosive gastritis, mosaic gastritis, as well as with both erosive and non-erosive duodenitis. No significant relationships were observed between <i>H. pylori</i> and demographic factors, atrophic, or nodular gastritis. (4) Conclusions: These findings underscore the importance of targeted testing and early eradication of <i>H. pylori</i> to manage gastritis effectively and reduce the risk of progression to more serious gastric conditions in the Lebanese population.