Rutaecarpine targets F-box and WD repeat domain containing 11 to inhibit inflammatory infiltration and alleviate acute pancreatitis
Collectively, our findings demonstrate that Rut ameliorates AP by upregulating EZH2, thereby enhancing H3 methylation and suppressing FBXW11 expression.
Authors
- Huan Gu (ORCID: https://orcid.org/0000-0001-7300-6997)
- Yan Jia (ORCID: https://orcid.org/0000-0003-1048-9842)
- Ya Liu (ORCID: https://orcid.org/0000-0002-7816-684X)
- Yan Lu (ORCID: https://orcid.org/0000-0002-4126-0082)
- Jie Peng (ORCID: https://orcid.org/0000-0002-6914-8260)
- Yuxin Shi (ORCID: https://orcid.org/0000-0002-1065-2809)
Institutions
- Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- World Journal of Gastroenterology
- Published
- 2025-10-13
- DOI
- https://doi.org/10.3748/wjg.v31.i38.109486
- Citations
- 1
- Primary Topic
- Cancer Mechanisms and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 1.47