Prophylactic Antibiotic Use in Transperineal Ultrasound-Guided Prostate Biopsy Under Local Anesthesia: A Retrospective Observational Study

In this cohort, the omission of prophylactic antibiotics during LATP prostate biopsy was not associated with an increased risk of infection. These findings support the safety of a no-antibiotic approach and highlight smoking as a potential risk factor for post-biopsy UTI. Broader adoption of selective antibiotic protocols may contribute to improved antimicrobial stewardship without compromising patient safety.