Nodular Growths of NF2-Related Schwannomatosis Vestibular Schwannoma: Clinical and Therapeutical Consequences

NF2-SWN VS display specific growth patterns different from sporadic VS, frequently with nodules, explained by the genetic of these tumors. The growth of a nodule in the posterior-inferior part was strongly and specifically correlated with hearing loss, probably because of the stretching of the cochlear nerve.

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Publication Details

Journal
Neurosurgery
Published
2025-10-13
DOI
https://doi.org/10.1227/neu.0000000000003801
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
Field-Weighted Citation Impact
0.00
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article

Nodular Growths of NF2-Related Schwannomatosis Vestibular Schwannoma: Clinical and Therapeutical Consequences

Frank D. Buono, Michel Kalamarides, Louise Deboeuf, Noemi Jester et al.
Neurosurgery
Neurofibromatosis and Schwannoma Cases
article

Nodular Growths of NF2-Related Schwannomatosis Vestibular Schwannoma: Clinical and Therapeutical Consequences

Frank D. Buono, Michel Kalamarides, Louise Deboeuf, Noemi Jester, Manwi Singh
article en

Abstract

NF2-SWN VS display specific growth patterns different from sporadic VS, frequently with nodules, explained by the genetic of these tumors. The growth of a nodule in the posterior-inferior part was strongly and specifically correlated with hearing loss, probably because of the stretching of the cochlear nerve.

Neurosurgery
Yale University (US), Sorbonne Université (FR), Assistance Publique – Hôpitaux de Paris (FR), Laboratoire National de Référence (MA), Pitié-Salpêtrière Hospital (FR), University of Sheffield (GB)
Openalex Percentile: Top 59%
Neurofibromatosis and Schwannoma Cases
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