One-year outcomes of trabeculectomy with mitomycin C in secondary glaucoma due to posner-schlossman syndrome

To explore the effectiveness and safety of surgical treatment for patients with Posner-Schlossman syndrome (PSS) accompanied by optic nerve Changes. A retrospective analysis was conducted on 15 cases (15 eyes) of glaucoma secondary to PSS who underwent trabeculectomy from January 2018 to March 2023 at Chongqing Aier Eye Hospital. Preoperative and postoperative conditions, as well as intraocular pressure (IOP) during postoperative recurrences, were compared. 15 eyes underwent trabeculectomy, with diffuse and mildly elevated filtering blebs postoperatively, without Choroidal detachment or macular edema. The preoperative IOP was 30.91 ± 11.75 mmHg (mean ± SD), and patients used 2.60 ± 0.91 types of antiglaucoma medication. At 12 months postsurgery, the mean IOP was 12.09 ± 2.33 mmHg, and no antiglaucoma medications were used thereafter (both P < 0.05). Nine eyes experienced recurrence of PSS, with IOP during recurrences being lower than preoperative levels. Except for one eye with an IOP of 24 mmHg, the other eight eyes had IOPs not exceeding 21 mmHg. Trabeculectomy is a safe and effective treatment for patients with PSS during episodes with optic nerve damage, and it can reduce the peak IOP during recurrences, preventing further optic nerve damage from high IOP.