Gastrointestinal adverse events associated with Hedgehog pathway inhibitors: a disproportionality analysis
HPIs had triggered various types of GIAEs. Liver injuries were a safety concern for the HPI-treated patient, which was not listed by the USFDA. Further researches are needed to confirm these findings.
Authors
- Mohammed Salim Karattuthodi (ORCID: https://orcid.org/0000-0002-8398-2737)
- Gouri Nair (ORCID: https://orcid.org/0000-0003-2081-6827)
- Shabeer Ali Thorakkattil (ORCID: https://orcid.org/0000-0002-4827-1972)
- Mahmathi Karuppannan (ORCID: https://orcid.org/0000-0002-6503-3191)
- Anjana Shenoy
- A. M. Shivakumar
Institutions
- Northeastern University (US)
- Manipal Academy of Higher Education (IN)
- Saudi Aramco Medical Services Organization (SA)
- M S Ramaiah University of Applied Sciences (IN)
- Universiti Teknologi MARA (MY)
Publication Details
- Journal
- International Journal of Pharmacy Practice
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1093/ijpp/riaf090
- Primary Topic
- Hedgehog Signaling Pathway Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00