Outside Back Cover: Reversing Lanmodulin's Metal‐Binding Sequence in Short Peptides Surprisingly Increases the Lanthanide Affinity (Angew. Chem. Int. Ed. 46/2025)
Lanmodulin-inspired Lanthanide-binding peptides synthesised in reversed order have a higher affinity to lanthanides than the natural sequence, as reported by Lena Daumann et al. in their Research Article (e202510453). As highlighted in this cover art the band of the cassette which gets rewound by the pencil symbolises the reversed peptides binding a trivalent europium. The original protein is shown as sketch in the back. That the higher affinity was a serendipitous finding is accentuated with the song title printed on the cassette.
Authors
- Robin Steudtner (ORCID: https://orcid.org/0000-0002-3103-9587)
- Sophie M. Gutenthaler (ORCID: https://orcid.org/0000-0002-8412-3328)
- Lena J. Daumann (ORCID: https://orcid.org/0000-0003-2197-136X)
- Satoru Tsushima (ORCID: https://orcid.org/0000-0002-4520-6147)
- Björn Drobot (ORCID: https://orcid.org/0000-0003-1245-0466)
- Jérôme Kretzschmar (ORCID: https://orcid.org/0000-0001-5042-8134)
Institutions
- Helmholtz-Zentrum Dresden-Rossendorf (DE)
- Japan Research Institute (JP)
- Heinrich Heine University Düsseldorf (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Angewandte Chemie International Edition
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1002/anie.202521814
- Primary Topic
- Chemical Synthesis and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00