Non-Traditional Topical Negative Pressure Applications

Topical negative pressure is one of the first treatment methods that comes to mind for chronic wound closure in recent years, and especially in reconstructive surgery, topical negative pressure therapy is a definitive treatment method that is frequently used. The purpose of this article is to compile non-traditional applications in the literature and to prompt scientists to form thoughts on the usability of this method in different areas. Considering the experimental and clinical research conducted for non-traditional topical negative pressure applications, although positive results were obtained in many of them, it is understood that more comprehensive research is required since there are not enough subjects or patients. We think that it can be applied to clinical practice, especially in the experimentally proven hypothermia-induced myocardial infarction and flap delay issues.