A Rare Case of Cervical Rhabdomyosarcoma in Adults

Cervical embryonal rhabdomyosarcoma is a rare mesenchymal solid tumor that accounts for less than 1% of all cervical neoplasms in the female genital system. There is no standardized protocol for the treatment of cervical embryonal rhabdomyosarcoma, and the literature primarily consists of case reports and series. Treatment options described in the literature range from conservative, fertility-preserving approaches to radical surgery in combination with chemotherapy and radiotherapy. A combined approach involving surgery, chemotherapy, and radiotherapy is believed to yield better outcomes for the disease. In this article, we present a case of cervical embryonal rhabdomyosarcoma in a 45-year-old female patient presenting with a polypoid cervical mass. Histopathological and immunohistochemical examination confirmed that the localized mass in the cervix was of cervical origin and consistent with embryonal rhabdomyosarcoma. Following total abdominal hysterectomy, the patient was administered a combination treatment of adjuvant chemoradiotherapy, and she has remained disease-free for a period of 23 months.

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Journal
Hitit Medical Journal
Published
2025-10-13
DOI
https://doi.org/10.52827/hititmedj.1683368
Primary Topic
Sarcoma Diagnosis and Treatment
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article
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article

A Rare Case of Cervical Rhabdomyosarcoma in Adults

Canan Kelten Talu, Muzaffer Şancı, Duygu Ayaz, Celal Akdemir et al.
Hitit Medical Journal
Sarcoma Diagnosis and Treatment
article

A Rare Case of Cervical Rhabdomyosarcoma in Adults

Canan Kelten Talu, Muzaffer Şancı, Duygu Ayaz, Celal Akdemir, Özgür Erdoğan, Mücahit Furkan Balcı, Halil İbrahim Yıldız
article en

Abstract

Cervical embryonal rhabdomyosarcoma is a rare mesenchymal solid tumor that accounts for less than 1% of all cervical neoplasms in the female genital system. There is no standardized protocol for the treatment of cervical embryonal rhabdomyosarcoma, and the literature primarily consists of case reports and series. Treatment options described in the literature range from conservative, fertility-preserving approaches to radical surgery in combination with chemotherapy and radiotherapy. A combined approach involving surgery, chemotherapy, and radiotherapy is believed to yield better outcomes for the disease. In this article, we present a case of cervical embryonal rhabdomyosarcoma in a 45-year-old female patient presenting with a polypoid cervical mass. Histopathological and immunohistochemical examination confirmed that the localized mass in the cervix was of cervical origin and consistent with embryonal rhabdomyosarcoma. Following total abdominal hysterectomy, the patient was administered a combination treatment of adjuvant chemoradiotherapy, and she has remained disease-free for a period of 23 months.

Hitit Medical JournalVol. 7(3)
Izmir University (TR), Education Training And Research (US)
Openalex Percentile: Top 59%
Sarcoma Diagnosis and Treatment
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A Rare Case of Cervical Rhabdomyosarcoma in Adults — Canan Kelten Talu, Muzaffer Şancı, et al. · Hitit Medical Journal (2025) | TGRS Research Map | TGRS