Hepatotoxicity risk factors in HIV-infected MSM with HBV/HCV coinfections: A cohort study in Northwestern China
HIV/HBV and HIV/HCV coinfections significantly increased the risk of hepatotoxicity in HIV-infected MSM receiving ART. These findings underscore the importance of vigilant liver function monitoring in coinfected patients on ART, particularly in consideration of baseline factors such as age, time to treatment, CD4 + T-cell count, and hemoglobin level, to minimize interruptions and optimize outcomes.
Authors
- Ruimin Bai (ORCID: https://orcid.org/0000-0002-1691-7521)
- Yan V. Sun (ORCID: https://orcid.org/0000-0002-2838-1824)
- T Y Wang
- Zirong Zhu
- Yan Zheng
- Xiaoying Ma (ORCID: https://orcid.org/0000-0002-1530-3536)
- Xinrong Zhao
Institutions
- The Fourth People's Hospital (CN)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Xi’an Children’s Hospital (CN)
- The Eighth Hospital of Xi'an (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1371/journal.pone.0333371
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China