MiR-376a-3p inhibits bone repair by regulating osteoblastic differentiation
We revealed the regulatory role of miR-376a-3p/WWTR1 in fracture nonunion by inhibiting osteogenic induction, which provides the possibility that miR-376a-3p may be a new underlying target for fracture nonunion prediction and therapy.
Authors
- Decheng Yang (ORCID: https://orcid.org/0000-0002-3177-0070)
- Fangyuan Zhang (ORCID: https://orcid.org/0000-0003-3840-9947)
- Jian Zhang (ORCID: https://orcid.org/0000-0003-1386-8792)
- Shuyang Jing (ORCID: https://orcid.org/0009-0000-1832-3981)
- Jinxiang Zhang (ORCID: https://orcid.org/0000-0002-5447-272X)
Institutions
- Southwest General Health Center (US)
- Qinhuangdao Second Hospital (CN)
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
- Baise University (CN)
- Chongqing Jiulongpo People's Hospital (CN)
- First Hospital of Qinhuangdao (CN)
- Yangzhou University (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1186/s13018-025-06291-0
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00