Clinical and Radiological Predictors for Early Hematoma Expansion After Spontaneous Intracerebral Hemorrhage: A Retrospective Study
Early hematoma expansion occurred in 13.4% of patients and was predicted by a combination of CTA and NCCT markers, as well as clinical and pharmacological factors. Spot sign remained the strongest predictor, while NCCT features such as blend sign and low hematoma density also provided practical prognostic value. These findings underscore the multifactorial pathophysiology of ICH expansion and highlight the importance of integrating imaging, clinical, and therapeutic variables into prediction models to improve early risk stratification and guide targeted interventions.
Authors
- Hark Rım (ORCID: https://orcid.org/0000-0002-6341-6711)
- Ji Hee Kim
- Jee Hye Wee (ORCID: https://orcid.org/0000-0002-6513-7011)
- Joon Ho Song (ORCID: https://orcid.org/0000-0003-3138-074X)
- In Bok Chang (ORCID: https://orcid.org/0000-0001-8003-3264)
- Yi Hwa Choi (ORCID: https://orcid.org/0000-0001-6055-3473)
- Young Seon Hong (ORCID: https://orcid.org/0000-0002-8132-719X)
- Eun Sun Kim (ORCID: https://orcid.org/0000-0003-1820-459X)
Institutions
- Hallym University (KR)
- Sacred Heart Hospital (US)
- Hallym University Medical Center (KR)
Publication Details
- Journal
- Neurology International
- Published
- 2025-10-12
- DOI
- https://doi.org/10.3390/neurolint17100170
- Citations
- 2
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 2.78