Additive effects of depression and abdominal obesity on cognitive function in middle-aged and older population: evidence from multinational cohorts
Abdominal obesity and depression exert independent additive and fluctuating effects on measures of cognition in middle-aged and older persons. Strategies that broadly aim to decrease excess fat, notably abdominal obesity, represent near-term interventions that may beneficially influence aspects of cognition in depression.
Authors
- Bing Cao (ORCID: https://orcid.org/0000-0001-5963-2676)
- Roger S. McIntyre (ORCID: https://orcid.org/0000-0003-4733-2523)
- Kayla M. Teopiz (ORCID: https://orcid.org/0000-0001-8429-6563)
- Yalin Chen (ORCID: https://orcid.org/0000-0002-3515-3360)
- Ruiqi Wang (ORCID: https://orcid.org/0000-0002-9403-7693)
Institutions
- Southwest University (CN)
- University of Toronto (CA)
- Brain and Cognition Discovery Foundation (CA)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1186/s12916-025-04298-2
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- National Natural Science Foundation of China