The Role of the JAK/STAT Pathway in the Pathogenesis and Treatment of Keloids: A Systematic Review
The JAK/STAT pathway plays a key role in keloid fibrogenesis. Although JAK inhibitors show promise, further research is needed to confirm efficacy, refine specificity, and minimize systemic risks. Targeted JAK/STAT inhibition may improve keloid treatment in dermatologic surgery.
Authors
- David Bitterman (ORCID: https://orcid.org/0009-0002-1857-8903)
- Neal Gupta
- Jared Jagdeo (ORCID: https://orcid.org/0000-0002-7619-7650)
- Kayla Zafar
- Margaret Kabakova
Institutions
- State University of New York (US)
- St. George's University (GD)
- New York Medical College (US)
- SUNY Downstate Health Sciences University (US)
- VA NY Harbor Healthcare System (US)
Publication Details
- Journal
- Dermatologic Surgery
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1097/dss.0000000000004903
- Primary Topic
- Dermatologic Treatments and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00