Figure 2 from Efficacy and Safety of Nivolumab Monotherapy in Patients with High PD-1–Positive CD8/Treg Ratio in Advanced NSCLC and Gastric Cancer: A Phase II, Multicenter Study
<p>Evaluation of PD-1<sup>+</sup> Treg cells and PD-1<sup>+</sup>CD8<sup>+</sup> T cells. <b>A</b> and <b>B,</b> The scatter plots that show PD-1 positivity (%) in CD8<sup>+</sup> T cells and Treg cells in patients with (<b>A</b>) NSCLC and (<b>B</b>) gastric cancer (GC). Straight line indicates PD-1 positivity (%) in CD8<sup>+</sup> T cells/PD-1 positivity (%) in Treg cells of ≥1.</p>
Authors
- Kyoichi Okishio (ORCID: https://orcid.org/0000-0002-6348-1302)
- Hiroki Izumi (ORCID: https://orcid.org/0000-0002-9566-4859)
- Kohei Shitara (ORCID: https://orcid.org/0000-0001-5196-3630)
- Hisashi Hosaka
- Kunihiro Tsuji (ORCID: https://orcid.org/0000-0001-7463-7272)
- Yukiya Narita (ORCID: https://orcid.org/0000-0002-8018-0077)
- Motohiro Tamiya (ORCID: https://orcid.org/0000-0001-6529-3092)
- Hiroki Hara (ORCID: https://orcid.org/0000-0003-3881-9815)
- Nobuhiko Seki (ORCID: https://orcid.org/0000-0002-6562-1137)
- Akihito Tsuji (ORCID: https://orcid.org/0000-0003-4034-1945)
- Yasunori Ushida
- Toshifumi Yamaguchi (ORCID: https://orcid.org/0000-0003-1399-1918)
- Hideaki Suna (ORCID: https://orcid.org/0000-0001-9202-316X)
- Kensei Yamaguchi (ORCID: https://orcid.org/0000-0001-6887-5709)
- Katsunori Shinozaki (ORCID: https://orcid.org/0000-0003-0596-3423)
- Hiroshi Tanaka (ORCID: https://orcid.org/0000-0002-8003-7326)
- Yosuke Tamura (ORCID: https://orcid.org/0009-0000-0513-2860)
- Naohiro Watanabe
- Takeshi Shiraishi (ORCID: https://orcid.org/0000-0001-9558-3576)
Publication Details
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1158/2767-9764.30344823
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00