<i>UBD</i> Promotes The Proliferation and Epithelial-Mesenchymal Transition of Hepatocellular Carcinomas via Regulating <i>CTNNA3</i>.

<i>UBD</i> plays an oncogenic role in HCC by encouraging proliferation and EMT through promoting CTNNA3 degradation. These findings suggest that targeting the <i>UBD</i>/<i>CTNNA3</i> axis could be a potential therapeutic strategy for HCC management.

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Publication Details

Journal
PubMed
Published
2025-09-30
DOI
https://doi.org/10.22074/cellj.2025.2045823.1724
Primary Topic
Epigenetics and DNA Methylation
Type
article
Field-Weighted Citation Impact
0.00
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article

UBD Promotes The Proliferation and Epithelial-Mesenchymal Transition of Hepatocellular Carcinomas via Regulating CTNNA3.

Yana Wang, Yong Du
PubMed
Epigenetics and DNA Methylation
article

UBD Promotes The Proliferation and Epithelial-Mesenchymal Transition of Hepatocellular Carcinomas via Regulating CTNNA3.

Yana Wang, Yong Du
article en

Abstract

<i>UBD</i> plays an oncogenic role in HCC by encouraging proliferation and EMT through promoting CTNNA3 degradation. These findings suggest that targeting the <i>UBD</i>/<i>CTNNA3</i> axis could be a potential therapeutic strategy for HCC management.

PubMedVol. 27(1)
Tongji University (CN), Shanghai Tenth People's Hospital (CN)
Openalex Percentile: Top 75%
Epigenetics and DNA Methylation
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