Estimated glucose disposal rate and the dynamic transitions of cardiometabolic multimorbidity and all-cause mortality in prediabetes: a multistate trajectory analysis
In individuals with prediabetes, higher insulin sensitivity is associated with a reduced risk of CMD, CMM, and all-cause mortality. Once the first CMD occurs, the association between eGDR and mortality becomes less pronounced, highlighting the critical importance of early intervention to improve insulin sensitivity.
Authors
- Pinfang Kang (ORCID: https://orcid.org/0000-0001-7084-7862)
- Xiaojun Feng (ORCID: https://orcid.org/0000-0003-2322-523X)
- Wenke Cheng
- Bi Tang (ORCID: https://orcid.org/0000-0001-6059-6713)
- Jinjun Liu (ORCID: https://orcid.org/0000-0002-4494-6602)
Institutions
- Bengbu Medical College (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1186/s12944-025-02699-z
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust
- Northwest Regional Development Agency
- Medical Research Council