Whole-genome sequencing of Lassa virus from dry blood spots: a comparative evaluation
Our study demonstrates that DBS is a viable alternative for whole genome sequencing of LASV, although whole blood samples consistently outperform DBS in terms of RNA concentration, Ct values and NGS coverage.
Authors
- Emma C. Thomson (ORCID: https://orcid.org/0000-0003-1482-0889)
- N’Faly Magassouba (ORCID: https://orcid.org/0000-0002-3760-6642)
- Christopher Davis (ORCID: https://orcid.org/0000-0002-7317-3266)
- Umaru Bangura (ORCID: https://orcid.org/0000-0001-8789-3187)
- Andreas Dahl (ORCID: https://orcid.org/0000-0002-2668-8371)
- Élisabeth Fichet-Calvet (ORCID: https://orcid.org/0000-0002-9421-3538)
- Sylvia Klemroth
Institutions
- Njala University (SL)
- MRC University of Glasgow Centre for Virus Research (GB)
- Center for Systems Biology Dresden (DE)
- Institut de Recherche Agronomique de Guinée (GN)
- Bernhard Nocht Institute for Tropical Medicine (DE)
Publication Details
- Journal
- Infectious Diseases of Poverty
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1186/s40249-025-01362-0
- Citations
- 1
- Primary Topic
- Viral Infections and Outbreaks Research
- Type
- article
- Field-Weighted Citation Impact
- 1.40