Thoughts on the application of sirolimus

that sirolimus may inhibit the growth of K562 cells via the SHP1/STAT3 pathway.However, due to differences in both the drugs and cell lines used, further experiments are needed to verify whether sirolimus acts through the SHP1/ STAT3 pathway in leukemia cell lines other than HEL (including K562).We are extremely grateful for the opportunity to share our views and would be happy to engage in academic exchanges.We are also very grateful to the authors for providing us with research ideas through their experimental results.

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Publication Details

Journal
Annals of Hematology
Published
2025-10-13
DOI
https://doi.org/10.1007/s00277-025-06660-z
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
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article

Thoughts on the application of sirolimus

Ying Liu, Yanna Zhao
Annals of Hematology
Renal Diseases and Glomerulopathies
article

Thoughts on the application of sirolimus

Ying Liu, Yanna Zhao
article en

Abstract

that sirolimus may inhibit the growth of K562 cells via the SHP1/STAT3 pathway.However, due to differences in both the drugs and cell lines used, further experiments are needed to verify whether sirolimus acts through the SHP1/ STAT3 pathway in leukemia cell lines other than HEL (including K562).We are extremely grateful for the opportunity to share our views and would be happy to engage in academic exchanges.We are also very grateful to the authors for providing us with research ideas through their experimental results.

Annals of HematologyVol. 104(11)
Zhejiang Chinese Medical University (CN), Zhejiang Provincial Hospital of TCM (CN), Zhejiang Hospital (CN)
Openalex Percentile: Top 70%
Renal Diseases and Glomerulopathies
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