Prevalence and clinical impact of Vitamin A Deficiency (VAD) in critically ill children with sepsis
Our cohort found that VAD is more prevalent in pediatric sepsis patients compared to controls and correlated with higher PRISM scores, sepsis severity and prolonged stays in PICUs. Nevertheless, VAD did not demonstrate a statistically significant association with 28-days mortality. These findings highlight the necessity for additional large-scale research to determine if routine screening of VAD and potential supplementation could improve outcomes in these patients.
Authors
- Ahmed S. Dabour (ORCID: https://orcid.org/0000-0002-5275-5734)
- Amany Mohammed El-Rebigi (ORCID: https://orcid.org/0000-0002-2020-1294)
- O.S. El-Shimi (ORCID: https://orcid.org/0000-0001-8276-8352)
- Rasha Mohammed Zakaria (ORCID: https://orcid.org/0009-0000-8915-4783)
- Amr Ibrahim
- Sara Hosny El-Farargy (ORCID: https://orcid.org/0000-0002-3691-7772)
Institutions
- Benha University (EG)
- Arab Open University (EG)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1186/s12887-025-06143-0
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Development Fund