Pharmacodynamic and Metabolomic Mechanism of Shexiang Baoxin Pill Based on <i>db/db</i> Mice on Treating Type 2 Diabetes Mellitus
SBP has a positive effect in regulating fasting glucose and insulin sensitivity in T2DM db/db mice, possibly through the FAO metabolic pathway. SBP in combination with Met may play a positive role in the inflammatory response. The results of this study may offer a theoretical foundation for the clinical application of SBP on T2DM and provide new insights for the research of traditional Chinese medicine in treating diseases.
Authors
- Zhicong Wang (ORCID: https://orcid.org/0000-0002-4238-9312)
- Zifan Zhu (ORCID: https://orcid.org/0000-0002-8443-5866)
- Bingrui Xie
- Lin Peng (ORCID: https://orcid.org/0009-0007-1220-0308)
- Xiang Li (ORCID: https://orcid.org/0000-0002-6378-9921)
- Runhui Liu (ORCID: https://orcid.org/0000-0001-7489-4957)
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
- Hong Kong Baptist University (HK)
- Naval University of Engineering (CN)
Publication Details
- Journal
- Rapid Communications in Mass Spectrometry
- Published
- 2025-10-12
- DOI
- https://doi.org/10.1002/rcm.10153
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00