Targeted next-generation sequencing using bronchoalveolar lavage fluid samples for diagnosing pulmonary infections: a single-center retrospective study
The sensitivity and accuracy of tNGS were better than those of culture and CMTs. tNGS results were critically associated with the development of clinical treatment plans for most patients. tNGS can be used as a rapid and accurate auxiliary diagnostic method, along with CMTs, for PIs.
Authors
- Heng Weng (ORCID: https://orcid.org/0000-0003-2547-773X)
- Hongyan Li (ORCID: https://orcid.org/0000-0003-3603-4045)
- Ling Ye (ORCID: https://orcid.org/0000-0003-0903-9377)
- Ying Lin (ORCID: https://orcid.org/0000-0003-2416-2154)
- Meiqin Jiang
- Baosong Xie (ORCID: https://orcid.org/0000-0002-4948-0063)
- Jinbao Huang (ORCID: https://orcid.org/0000-0002-1248-0019)
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
- Fujian Medical University (CN)
- Fujian Provincial Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-10-13
- DOI
- https://doi.org/10.3389/fmicb.2025.1671819
- Citations
- 1
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Fujian University of Traditional Chinese Medicine