Real-life evaluation of the effectiveness of biologics for chronic rhinosinusitis with nasal polyps in Europe: a Delphi study to define key variables for the INVENT registry
This international Delphi study identified a consensus-based set of clinically-relevant and feasible variables for inclusion in the INVENT registry. The selected variables reflect current best practices in the management of CRSwNP and will enable robust comparisons of biologic effectiveness in real-world settings. The INVENT registry is well-positioned to inform treatment decisions, optimize use of biologics, and support a personalized approach to CRSwNP care.
Authors
- Jannis Constantinidis (ORCID: https://orcid.org/0000-0002-2369-993X)
- Emmanuel Prokopakis (ORCID: https://orcid.org/0000-0002-1208-1990)
- Eliza Brożek-Mądry (ORCID: https://orcid.org/0000-0003-3113-3079)
- Wytske J. Fokkens (ORCID: https://orcid.org/0000-0003-4852-229X)
- Marjolein Cornet
- Peter W. Hellings (ORCID: https://orcid.org/0000-0001-6898-688X)
- Martin Wagenmann
- Peter G. Gibson (ORCID: https://orcid.org/0000-0001-5865-489X)
- Michael B. Soyka
- Eugenio De Corso (ORCID: https://orcid.org/0000-0001-5761-7018)
- Adam Chaker (ORCID: https://orcid.org/0000-0002-5117-4073)
- Sietze Reitsma (ORCID: https://orcid.org/0000-0003-1734-2632)
- Anette Drøhse Kjeldsen (ORCID: https://orcid.org/0000-0003-0593-6302)
- Christian von Buchwald (ORCID: https://orcid.org/0000-0001-6753-8129)
- Aleksander Grande Hansen (ORCID: https://orcid.org/0000-0001-9862-0811)
- G. Mortuaire (ORCID: https://orcid.org/0000-0002-1592-1625)
- Émilie Béquignon
- Philippe Gevaert (ORCID: https://orcid.org/0000-0002-1629-8468)
- Vibeke Backer (ORCID: https://orcid.org/0000-0002-7806-7219)
- Luísa Azevedo (ORCID: https://orcid.org/0000-0002-4166-1230)
- Sanna Toppila‐Salmi (ORCID: https://orcid.org/0000-0003-0890-6686)
- Joaquim Mullol
Institutions
- University of Copenhagen (DK)
- University of Crete (GR)
- University of Eastern Finland (FI)
- University of Southern Denmark (DK)
- University of Zurich (CH)
- Universitair Ziekenhuis Leuven (BE)
- John Hunter Hospital (AU)
- AHEPA University Hospital (GR)
- Odense University Hospital (DK)
- Agostino Gemelli University Polyclinic (IT)
- Rigshospitalet (DK)
- Ghent University (BE)
- Hunter Medical Research Institute (AU)
- Düsseldorf University Hospital (DE)
- University Hospital Foundation (CA)
- University Hospital of Zurich (CH)
- Alrijne Ziekenhuis (NL)
- Lovisenberg Diakonale Høgskole (NO)
- Administração Regional de Saúde de Lisboa e Vale do Tejo (PT)
- Hospital Clínic de Barcelona (ES)
- Lille Inflammation Research International Center (FR)
- Ministry of Interior and Administration (PL)
- See-Spital (CH)
- Stadtspital Waid (CH)
- Amsterdam University Medical Centers (NL)
- Hôpital Intercommunal de Créteil (FR)
- Heinrich Heine University Düsseldorf (DE)
- Technical University of Munich (DE)
- University of Newcastle Australia (AU)
- KU Leuven (BE)
Publication Details
- Journal
- Frontiers in Allergy
- Published
- 2025-10-13
- DOI
- https://doi.org/10.3389/falgy.2025.1680703
- Citations
- 1
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 1.85
Funders
- Sanofi
- Regeneron Pharmaceuticals