Zinc deficiency and risk of intracerebral hemorrhage: a retrospective cohort study
Zinc deficiency is a novel, independent, and potentially modifiable risk factor for ICH. The dose-dependent relationship and consistency across patient populations supports biological plausibility. These findings suggest that routine zinc assessment and targeted supplementation in deficient patients may offer new opportunities for ICH prevention, warranting prospective intervention trials to establish causality and optimal therapeutic strategies.
Authors
- Jheng-Yan Wu
- Chun‐Ning Ho (ORCID: https://orcid.org/0000-0001-6469-226X)
- Shu-Wei Liao
- I‐Wen Chen (ORCID: https://orcid.org/0009-0004-7122-6901)
- Yi-Chen Lai (ORCID: https://orcid.org/0000-0002-8422-5797)
- Kuo-Chuan Hung
- Hsiu-Lan Weng
Institutions
- E-Da Hospital (TW)
- Chi Mei Medical Center (TW)
- Chia Nan University of Pharmacy and Science (TW)
- I-Shou University (TW)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-10-13
- DOI
- https://doi.org/10.3389/fnut.2025.1660475
- Citations
- 1
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 1.39